Test de performance anti - mousse diméthicone wrist oscillator

Cet oscillateur au poignet est spécialement conçu pour tester les propriétés anti - mousse de diméthicone, conformément aux exigences de la pharmacopée américaine.

Paramètres techniques:

Distance: 13,3 cm

Nombre de conteneurs: 2 x 2

Fréquence: 300RPM

Amplitude: 0 - 15o réglable

Minuterie (en option): 0.01s-99.99min

Dimensions extérieures: 55 x 40 x 32cm

Joint: Dimethicone Oil (simethicone) propriétés anti - mousse méthode d'essai de la pharmacopée américaine

Defoaming Activity
Foaming solution: 10 mg/mL of octoxynol 9 in water
Sample solution: 4 mg/mL of Simethicone in tertiary butyl alcohol. Shake vigorously.[Note—Warm slightly, if necessary, to dissolve. ]
Analysis
[Note—For each test, use a clean, unused, 250-mL glass jar. ]
Add, dropwise, 500 μL of the Sample solution to a clean, unused, cylindrical 250-mL glass jar, fitted with a 50-mm cap, containing 100 mL of the Foaming solution. Cap the jar, and clamp it in an upright position on a wrist-action shaker. Using a radius of 13.3 ± 0,4 cm (measured from the center of the shaft to the center of the bottle), shake for 10 s through an arc of 10 at a frequency of 300 ± 30 strokes/min. Record the time required for the foam to collapse. The time, in s, for foam collapse is determined at the instant the first portion of foam-free liquid surface appears, measured from the end of the shaking period.
Acceptance criteria: The defoaming activity time does not exceed 15 s.